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Active ingredient: Levodopa carbidopa

Sinemet - a combined remedy based on Levodopum + Carbidopum. In the treatment of Parkinson's syndrome and disease, Sinemet proved to be one of the most effective drug. The reviews are mostly positive, because it allows to reduce "inhibition" in patients who have been treated with other medications. For each patient, the dosage is selected individually, together with the frequency of admission.

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Availability: In Stock (118 packs)
Sinemet 250mg
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30 Pills $1.86 $55.88 - Add to cart
60 Pills $1.53 $111.65 $91.85 $19.80 Add to cart
90 Pills $1.35 $167.44 $121.54 $45.90 Add to cart
120 Pills $1.21 $222.97 $144.97 $78.00 Add to cart
180 Pills $1.02 $333.94 $182.74 $151.20 Add to cart
360 Pills $0.88 free-shipping $668.71 $315.91 $352.80 Add to cart
Sinemet 500mg
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30 Pills $2.22 $66.65 - Add to cart
60 Pills $1.82 $132.92 $108.92 $24.00 Add to cart
90 Pills $1.74 $199.83 $156.63 $43.20 Add to cart
120 Pills $1.69 free-shipping $266.13 $202.53 $63.60 Add to cart
180 Pills $1.63 free-shipping $399.66 $293.46 $106.20 Add to cart
360 Pills $1.57 free-shipping $800.14 $566.14 $234.00 Add to cart

Sinemet Product Description

Drug Uses

Sinemet is a combination drug related to a therapeutic class known as antiparkinsonian agents. Sinemet is used to manage rare and more common forms of parkinsonism or parkinsonian syndrome, such as:

Parkinson's disease (PD)

Symptomatic and post-encephalitic parkinsonism

Sinemet stops or reduces progression of parkinsonism symptoms, including symptoms that can result in disability. This effect is achieved because Sinemet improves the process of replenishing dopamine in the brain.

At the beginning of the parkinsonian syndrome treatment, one tablet of Sinemet 25/ 100mg should be taken, three times a day. The dosage can be increased by one tablet every 24 or 48 hours till the maximum recommended daily Sinemet dosage of eight 25/100mg tablets is achieved.

Missed dose

If you’ve missed the assigned dosage of Sinemet, take the antiparkinsonian agent as soon as you remember. However, do not take Sinemet if it is time for the next prescribed dosage of this drug. Return to regular dosing schedule of Sinemet on the next day.

More Information

Combined dopaminergic drug Sinemet starts acting within first days of treatment, and sometimes even after the first dose intake. The clinically significant antiparkinsonian effect is achieved within 7-10 days after initiating Sinemet-therapy.

Antiparkinsonian agent Sinemet should be protected from strong light and excessive moisture under 30°C, and kept in an original package thoroughly sealed.

Sinemet Safety Information


Sinemet should not be used if movement disorders, changes in behavior, hyperkinesia, and other extrapyramidal reactions were caused by drugs. In rare cases, the use of combined dopaminergic drug Sinemet may cause severe drowsiness, even in the middle of the day. Usually involuntary sleep episodes appear at the beginning of the parkinsonism treatment.

Information about treatment of Parkinson's disease, provided in this review of Sinemet, is offered only “as-is” for informational and educational purposes only. This information is not implied to be a substitute for professional medical advice of the neurologist, neurosurgeon or other medical professional. The online pharmacy shall not be liable for any injury, which may be caused by improper use of the information on antiparkinsonian agent Sinemet.

Sinemet Side Effects

Most adverse reactions of Sinemet are mild and normally disappear after the daily dosage of the antiparkinsonian agent is decreased. The most often Sinemet may cause in the patients with parkinsonism such reactions as dyskinesia, chest pain, low blood pressure, vomiting, gastrointestinal bleeding, nausea, angioedema, shortness of breath, flushing, loss of hair, back pain or shoulder pain.

In rare cases, the patients taking Sinemet complain of: asthenia, anorexia, diarrhea, dark saliva, palpitation, muscle cramps, low platelet count, urticaria, pruritus, dizziness, somnolence, urinary tract infection or swelling.

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